Thursday, February 20, 2020

Theories on the History of Science as Social Constructs Essay

Theories on the History of Science as Social Constructs - Essay Example l description of Hess’s concepts related to the cultural construction of science and technology, this paper moves towards a comparison between the theories of Carolyn Merchant and Hess. Both of them have their own ideas related to science, technology and nature. Merchant takes a feminist stance in her description of science and technology. At the end, a conclusion is given that summarizes the overall paper. T.S. Kuhn is his book, â€Å"The Structure of Scientific Revolutions†, evaluates the history of Science. Kuhn illustrates that science has not developed from accretion of factual information but from continuous transforming situations and probabilities for the people related to scientific disciplines (Polsby, 1998). For Kuhn, science that was prevalent in different eras of history was an output of the factors at that time (Polsby, 1998). Kuhn divided the history of science in three phases. In the first phase, there was no agreement on a single theory and people differ from each other in terms of suggested theories due to which, the theories of this phase were left deficient (Kuhn, 1962). Second phase saw some acceptance on theories and there was proper experimentation and analysis (Kuhn, 1962). Kuhn regards the third phase of science as innovatory and revolutionary (Kuhn, 1962). According to Kuhn, science moves between these phases to get some results (Kuhn, 1962). The movie, â€Å"Mindwalk† directed by Bernt Amadeus Capra introduces three characters who are involved in a correspondence. First one is a politician; second one is a scientist while the third one is a poet. Each of them has a diverse viewpoint and sees the world differently. The movie is based on Kuhn ideas that are linked to the discovery of new concepts in scientific field. The movie illustrates that people should not rely on old discoveries and theories, they should revolutionize and should move towards new grounds. As Kuhn has explained that, every scientific development has three phases,

Tuesday, February 4, 2020

Concise scientific report on mobilisation and harvest of haemopoietic Research Paper

Concise scientific report on mobilisation and harvest of haemopoietic stem cells - Research Paper Example Transplantation of genetically identical marrow or the animals own stored marrow prevented death. These was applied by Thomas and his colleagues in 1959 in treatment of leukaemia in humans. Survival was also permitted by grafts from histo-compatible donors. In the early 1960s, allogeneic transplantation became feasible after the identification and typing of human leucocyte antigen (HLA). This work provided basis for the understanding hematopoietic stem cell transplantation. Haematopoietic stem cells produce some daughter cells that retain stem cell properties. Primitive progenitors produce mature blood cells are continuously produced by less differentiated precursors which descend from the haematopoietic stem cells. In a lethally irradiated animal, a single stem cell can restore an entire lympho-hematopoietic system (Copelan, 2006). Since 2001, there has been an increase in the number of transplants occurring annually (Passweg, et al., 2014). However, when the histocompatibility antigens of the donor and the recipient are incompatible, there could be strong transplant reactions and the intensity increases with the multiple peptides generation from the degraded HLA molecules and in the presence of determinants on the HLA molecules that are recognisable on the cell surface of the cells presenting the antigen. When an immune response is stimulated, an injury referred to as graft-versus host disease (GVHD) occurs due to the preparative regimen used before transplantation causing injury (Copelan, 2006). Haematopoietic stem cell transplant is usually successful if there is a positive outcome. Many diseases are treated with either autologous or allogeneic haematopoietic stem cell transplantation. The type and stage of the disease, the age and functional level of the patient, the source of the stem cell to be transplanted and the degree of mismatch of HLA affect the outcome (Dainiak & Ricks, 2014). The autologous transplantation improves survival rather